Diagnosis and treatment


A physical examination is often sufficient to identify the presence of scar weave in the penis and diagnose Peyronie ‘s disease. rarely, other conditions cause similar symptoms and need to be ruled out .
Tests to diagnose Peyronie ‘s disease and understand precisely what ‘s causing your symptoms might include the following :

  • Physical exam. Your doctor will feel ( palpate ) your penis when it ‘s not erect, to identify the location and sum of scratch tissue. He or she might besides measure the duration of your penis. If the discipline continues to worsen, this initial measurement helps determine whether the penis has shortened.

    Your doctor might besides ask you to bring in photos of your erect penis taken at base. This can determine the degree of curvature, placement of scratch tissue or early details that might help identify the best treatment approach .

  • Other tests. Your doctor might order an ultrasound or early tests to examine your penis when it ‘s tumid. Before testing, you ‘ll probable receive an injection directly into the penis that causes it to become rear .
    sonography is the most normally used quiz for penis abnormalities. ultrasound tests use sound waves to produce images of soft tissues. These tests can show the presence of scratch tissue, blood menstruate to the penis and any other abnormalities .

Care at Mayo Clinic

Our caring team of Mayo Clinic experts can help you with your Peyronie ‘s disease-related health concerns Start hera


treatment recommendations for Peyronie ‘s disease count on how long it ‘s been since you began having symptoms .

  • Acute phase. You have penile pain or changes in curvature or length or a deformity of the penis. The acute phase happens early in the disease and may last only two to four weeks but sometimes lasts for up to a year or longer.
  • Chronic phase. Your symptoms are stable, and you have no penile pain or changes in curvature, length or deformity of the penis. The chronic phase happens later in the disease and generally occurs around three to 12 months after symptoms begin.

For the acute phase of the disease, treatments range from :

  • Recommended. When used early in the disease process, penile traction therapy prevents length loss and minimizes the extent of curvature that occurs.
  • Optional. Medical and injection therapies are optional in this phase, with some more effective than others.
  • Not recommended. Surgery isn’t recommended until the disease stabilizes, to avoid the need for repeat surgery.

For the chronic phase of the disease, several electric potential treatments are available. They may be done alone or in combination :

  • Watchful waiting
  • Injection treatments
  • Traction therapy
  • Surgery

oral medications are n’t recommended in the chronic phase, as they have n’t been shown to be effective at this stage of the disease. Shock wave therapy, stalk cells and platelet-rich plasma besides have n’t been shown to be effective in homo studies .


A number of oral medications have been tried to treat Peyronie ‘s disease, but they have not been shown to be effective systematically and are not vitamin a effective as operating room .
In some men, drugs injected immediately into the penis might reduce curvature and trouble associated with Peyronie ‘s disease. Depending on the therapy, you might be given a local anesthetic to prevent annoyance during the injections .
If you have one of these treatments, you ‘ll likely receive multiple injections over several months. Injection medications may besides be used in combination with oral drugs or grip therapies .
Medications include :

  • Collagenase. The lone FDA-approved medication for Peyronie ‘s disease is collagenase clostridium histolyticum ( Xiaflex ). This medicate has been approved for function in adult men with control to dangerous curvatures and a palpable nodule .
    This therapy has been shown to improve curvature and annoying symptoms associated with Peyronie ‘s disease. The treatment works by breaking down the buildup of collagen that causes penile curvature. Collagenase appears to be more effective when used in conjunction with “ model, ” which is forcible bend of the penis in the opposite management of the flex .
  • Verapamil. This is a drug normally used to treat high blood pressure. It appears to disrupt the production of collagen, a protein that might be a key factor in the formation of Peyronie’s disease scar tissue. The drug is well tolerated and may reduce pain, too.
  • Interferon. This is a type of protein that appears to disrupt the production of fibrous tissue and help break it down. One placebo-controlled trial showed improvement using this therapy over placebo. Interferon also has been shown to reduce penile pain in men with Peyronie’s disease.

Traction therapy

Penile traction therapy

Penile traction device and method

Penile traction therapy

With penile grip therapy, you wear a penile grip device for a set come of time each day. The device may stretch the penis straight out, or it may stretch the penis in the steering that ‘s opposite of the curvature .
Penile traction therapy involves stretching the penis with a self-applied mechanical device for a menstruation of time to improve penile length, curvature and deformity .
Depending on the specific device, traction therapy may need to be worn for angstrom little as 30 minutes to deoxyadenosine monophosphate much as three to eight hours a day to achieve benefits. The potency of treatment may besides depend on the specific device used .
grip therapy is recommended in the early on phase of Peyronie ‘s disease. It ‘s the only treatment shown to improve penile distance. Traction therapy may besides be used in the chronic phase of the disease, combined with early treatments or after operating room for a better consequence .


Plication of the penis

Plication procedure of the penis to correct curvature

Plication of the penis

During plication of the penis, an artificial erection is created from either injection of a seawater solution or selected medications. The extinct bark of the penis is pulled back. The penis is straightened, and the surfeit weave on what had been the forbidden side of the curve is cinched together by placing a series of stitches or “ tucks. ” The final examination penile length will depend on the distance of the short side — the side with the scarring from Peyronie ‘s disease .

Graft repair of the penis

Graft repair of the penis to correct curvature or other deformity

Graft repair of the penis

During a transplant rectify procedure, your surgeon makes one or more cuts ( incisions ) in the scar tissue ( brass ) of the penis, allowing the sheath to stretch out and the penis to straighten. A bandage made of human or animal tissue or a synthetic material is placed to cover the blemish .
Your doctor might suggest operating room if the deformity of your penis is austere, sufficiently bothersome or prevents you from having sex. Surgery normally is n’t recommended until you ‘ve had the condition for nine to 12 months and the curvature of your penis stops increasing and stabilizes for at least three to six months .
common surgical methods include :

  • Suturing (plicating) the unaffected side. A variety show of procedures can be used to suture ( pleat ) the longer side of the penis — the side without scratch weave. This results in a straighten of the penis, although this is frequently limited to less dangerous curvatures .
    several plication techniques may be used, generally resulting in like success rates depending on surgeon feel and predilection .
  • Incision or excision and grafting. With this type of surgery, the surgeon makes one or more cuts in the scar tissue, allowing the sheath to stretch out and the penis to straighten. The surgeon might remove some of the scar tissue .
    A objet d’art of tissue ( bribery ) is often sew into invest to cover the holes in the tunic albuginea. The bribery might be tissue from your own body, human or animal tissue, or a synthetic material .
    This routine is broadly used in men with more-severe curvature or disfigurement, such as indentations. This routine is associated with greater risks of worsening erectile function when compared with the plication procedures .
  • Penile implants. surgically placed penile implants are inserted into the spongy weave that fills with blood during an erecting. The implants might be semirigid — manually bent down most of the meter and bent up for sexual sexual intercourse .
    Another type of implant is inflated with a pump implanted in the scrotum. Penile implants might be considered if you have both Peyronie ‘s disease and erectile dysfunction .
    When the implants are put in target, the surgeon might perform extra procedures to improve the curvature if needed.

The type of operating room used will depend on your condition. Your doctor will consider the location of scar tissue, the austereness of your symptoms and other factors. If you ‘re uncircumcised, your doctor might recommend a circumcision during surgery .
Depending on the type of operating room you have, you might be able to go home from the hospital the like day or you might need to stay overnight. Your surgeon will advise you on how long you should wait before going bet on to work — broadly, a few days. After operating room for Peyronie ‘s disease, you ‘ll need to wait four to eight weeks before intimate bodily process .

Other treatments

A proficiency known as iontophoresis uses an electric current to administer a combination of verapamil and a steroid hormone noninvasively through the skin. available research has shown conflicting results on penile curvature and erectile routine .
several nondrug treatments for Peyronie ‘s disease are being investigated, but testify is limited on how well they work and possible side effects. These include using intense good waves to break up scratch tissue ( electric shock wave therapy ), stalk cells, platelet-rich plasma and radiation sickness therapy .
Peyronie ‘s disease wish at Mayo Clinic
Our caring team of Mayo Clinic experts can help you with your health concerns. Visit Mayo Clinic Men ‘s Health to get started .
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Clinical trials

explore Mayo Clinic studies testing new treatments, interventions and tests as a mean to prevent, detect, cover or wield this condition .

Coping and support

Peyronie ‘s disease can be a informant of significant anxiety and create tension between you and your sexual partner .
here are some tips for coping with Peyronie ‘s disease :

  • Explain to your partner what Peyronie’s disease is and how it affects your ability to have sex.
  • Let your partner know how you feel about the appearance of your penis and your ability to have sex.
  • Talk to your partner about how the two of you can maintain sexual and physical intimacy.
  • Talk to a mental health provider who specializes in family relations and sexual matters.

Preparing for your appointment

If you have Peyronie ‘s disease symptoms, you ‘re likely to begin by seeing your family repair or general practitioner. You might be referred to a specialist in male intimate disorders ( urologist ). If it ‘s possible, encourage your spouse to attend the appointment with you .
Preparing for your appointee will help you make the best manipulation of your time .

What you can do

Make a list ahead of meter that you can share with your sophisticate. Your number should include :

  • Symptoms you’re experiencing, including any that might seem unrelated to Peyronie’s disease
  • Key personal information, including any major stresses or recent life changes
  • Medications that you’re taking, including any vitamins or supplements
  • History of injury to the penis
  • Family history of Peyronie’s disease, if any
  • Questions to ask your doctor

list questions for your repair from most authoritative to least significant in lawsuit time runs out. You might want to ask some of the stick to questions :

  • What tests will I need?
  • What treatment do you recommend?
  • Can you tell if symptoms are likely to worsen or improve?
  • Are there any brochures or other printed material that I can take home with me? What websites do you recommend?

In addition to the questions you ‘ve prepared to ask your doctor, do n’t hesitate to ask questions during your appointment .

What to expect from your doctor

Your doctor is probably to ask you a count of questions. Being fix to answer them might reserve clock to go over any points you want to discuss far. Your doctor might ask :

  • When did you first notice a curve in your penis or scar tissue under the skin of your penis?
  • Has the curvature of your penis worsened over time?
  • Do you have pain during erections, and if so, has it gotten worse or improved over time?
  • Do you recall having an injury to your penis?
  • Do your symptoms limit your ability to have sex?

Your doctor of the church might besides ask you to complete a survey, such as the International Index of Erectile Function, to help identify how the condition affects your ability to have sex .
Peyronie ‘s disease care at Mayo Clinic
Our caring team of Mayo Clinic experts can help you with your health concerns. Visit Mayo Clinic Men ‘s Health to get started .
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