Non-communicable disease – Wikipedia

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Non-communicable disease
A nurse with a non-communicable diseases kit, Fiji, 2012. Photo- DFAT (13253315924).jpg
A nurse with a non-communicable diseases kit, Fiji, 2012.

A non-communicable disease ( NCD ) is a disease that is not ancestral directly from one person to another. NCDs include Parkinson ‘s disease, autoimmune diseases, strokes, most heart diseases, most cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer ‘s disease, cataracts, and others. NCDs may be chronic or acute. Most are non- infectious, although there are some non-communicable infectious diseases, such as parasitic diseases in which the leech ‘s animation cycle does not include address host-to-host transmission. NCDs are the leading cause of death globally. In 2012, they caused 68 % of all deaths ( 38 million ) up from 60 % in 2000. [ 1 ] About half were under historic period 70 and half were women. [ 2 ] Risk factors such as a person ‘s background, life style and environment increase the likelihood of certain NCDs. Every year, at least 5 million people die because of tobacco use and about 2.8 million die from being overweight. High cholesterol accounts for approximately 2.6 million deaths and 7.5 million die because of high lineage pressure.

risk factors

risk factors such as a person ‘s backdrop ; lifestyle and environment are known to increase the likelihood of certain non-communicable diseases. They include age, sex, genetics, exposure to air befoulment, and behaviors such as smoke, unhealthy diet and physical inactiveness which can lead to high blood pressure and fleshiness, in turn leading to increased gamble of many NCDs. Most NCDs are considered preventable because they are caused by modifiable risk factors. The WHO ‘s World Health Report 2002 identified five authoritative risk factors for non-communicable disease in the crown ten leading risks to health. These are raised blood pressure, raised cholesterol, tobacco manipulation, alcohol consumption, and being overweight. The other factors associated with higher hazard of NCDs include a person ‘s economic and social conditions, besides known as the sociable determinants of health. It has been estimated that if the primary hazard factors were eliminated, 80 % of the cases of heart disease, stroke and type 2 diabetes and 40 % of cancers could be prevented. Interventions targeting the main hazard factors could have a meaning affect on reducing the effect of disease cosmopolitan. Efforts focused on better diet and increased physical action have been shown to control the prevalence of NCDs .

environmental diseases

NCDs include many environmental diseases covering a wide class of evitable and ineluctable human health conditions caused by external factors, such as sunlight, nutriment, pollution, and life style choices. The diseases of affluence are non-infectious diseases with environmental causes. Examples include :

Inherited diseases

familial disorders are caused by errors in genic information that produce diseases in the affect people. The origin of these genetic errors can be :

  • Spontaneous errors or mutations to the genome:
  • A change in chromosome numbers, such as Down syndrome.
  • A defect in a gene caused by mutation, such as Cystic fibrosis.
  • An increase in the amount of genetic information, such as Chimerism or Heterochromia.

cystic fibrosis is an exercise of an familial disease that is caused by a mutant on a gene. The defective gene impairs the normal movement of sodium chloride in and out of cells, which causes the mucus-secreting organs to produce abnormally blockheaded mucus. The gene is recessionary, meaning that a person must have two copies of the defective gene for them to develop the disease. cystic fibrosis affects the respiratory, digestive and generative systems, deoxyadenosine monophosphate well as the fret glands. The mucus secreted is identical thick and blocks passageways in the lungs and digestive tracts. This mucus causes problems with breathe and with the digestion and absorption of nutrients .

  • Inherited genetic errors from parents:
  • Dominant genetic diseases, such as Huntingtons, require the inheritance of one erroneous gene to be expressed.
  • Recessive genetic diseases require the inheritance of erroneous genes to be expressed and this is one reason they work together.

Global health




















8,880-13,667 Deaths from noncommunicable diseases per million persons in 2012 Referred to as a “ life style ” disease, because the majority of these diseases are preventable illnesses, the most common causes for non-communicable diseases ( NCD ) include tobacco practice ( smoking ), hazardous alcohol use, inadequate diets ( high consumption of boodle, salt, saturated fats, and trans fatso acids ) and physical inaction. Currently, NCD kills 36 million people a class, a number that by some estimates is expected to rise by 17–24 % within the following ten. [ 3 ] historically, many NCDs were associated with economic development and were alleged a “ diseases of the rich “. The burden of non-communicable diseases in developing countries has increased however, with an estimated 80 % of the four independent types of NCDs — cardiovascular diseases, cancers, chronic respiratory diseases and diabetes — immediately occurring in low- and middle-income countries. natural process plan for the Global Strategy for the Prevention and Control of non-communicable Diseases and with two-thirds of people who are affected by diabetes now residing in developing nations, NCD can no longer be considered good a trouble affecting affluent estimate of the economic affect of chronic non-communicable diseases in selected countries. New WHO report : deaths from non-communicable diseases are on the rise, with developing universe reach unvoiced. As previously stated, in 2008 alone, NCD ‘s were the cause of 63 % of deaths global ; a number that is expected to rise well in the approximate future if measures are not taken. If present growth trends are maintained, by 2020, NCDs will attribute to 7 out of every 10 deaths in developing countries, killing 52 million people per annum cosmopolitan by 2030. With statistics such as these, it comes as no surprise that external entities such as the World Health Organization & World Bank Human Development Network have identified the prevention and control of NCDs as an increasingly crucial discussion item on the global health agenda. thus, should policy makers and communities mobilize “ and make prevention and targeted treatment of such diseases a precedence, ” sustainable measures can be implemented to stagnate ( and finally even reverse ) this emerging ball-shaped health threat. electric potential measures presently being discussed by the ( World Health Organization ) -Food and Agriculture Organization includes reducing the levels of salt in foods, limiting inappropriate commercialize of unhealthy foods and non-alcoholic beverages to children, imposing controls on harmful alcohol use, raising taxes on tobacco, and legislating to curb smoke in public places .

United Nations

The World Health Organization is the specialize agency of the United Nations ( UN ) that acts as coordinating authority on international populace health issues, including NCDs. In May 2008, the 193 Member States of the WHO approved a six-year plan to address non-communicable diseases, particularly the quickly increasing charge in low- and middle-income countries. The plan calls for raising the precedence given to NCDs in international growth bring ‘. During the 64th session of the United Nations General Assembly in 2010, a settlement was passed to call for a high-level meeting of the General Assembly on the prevention and treatment NCDs with the participation of heads of state of matter and government. The resolution besides encouraged UN Member States to address the issue of non-communicable diseases at the 2010 Review Summit for the Millennium Development Goals .

global Non-communicable Disease Network

In order to better coordinate efforts around the earth, in 2009 the WHO announced the establish of the Global Non-communicable Disease Network ( NCDnet ). [ 4 ] NCDnet will consist of leading health organizations and experts from around the worldly concern in order to fight against diseases such as cancer, cardiovascular disease, and diabetes. Ala Alwan, adjunct director-general for Non-communicable Diseases and Mental Health at the WHO, said : “ integrating the prevention of non-communicable diseases and injuries into the national and global development agendas is not only accomplishable but besides a priority for developing countries. ” [ 5 ]

NCD Alliance

The NCD Alliance is a ball-shaped partnership founded in May 2009 by four international federations representing cardiovascular disease, diabetes, cancer, and chronic respiratory disease. The NCD Alliance brings together roughly 900 national member associations to fight non-communicable disease. long term aims of the Alliance include : [ 6 ]

  1. NCD/disease national plans for all
  2. A tobacco free world
  3. Improved lifestyles
  4. Strengthened health systems
  5. Global access to affordable and good quality medicines and technologies
  6. Human rights for people with NCDs.

United Nations Interagency Task Force on the Prevention and Control of Non-communicable Diseases ( UNIATF )

The United Nations Interagency Task Force on the Prevention and Control of Non-communicable Diseases ( UNIATF ) was established by the United Nations Secretary-General in 2013 in order to provide scaled up action across the UN system to support governments, in particular in low- and middle-income countries, to tackle non-communicable diseases ( NCDs ) .

young Professionals Chronic Disease Network

The Young Professionals Chronic Disease Network, or normally referred to as YP-CDN, is a ball-shaped network of approximately 5000 young professionals across 157 countries. The organization aims to mobilize these new people “ to take action against social injustice driven by NCDs. “. [ 7 ]


previously, chronic NCDs were considered a problem limited largely to high income countries, while infectious diseases seemed to affect low income countries. The effect of disease attributed to NCDs has been estimated at 85 % in industrialize nations, 70 % in middle income nations, and closely 50 % in countries with the lowest national incomes. [ 8 ] In 2008, chronic NCDs accounted for more than 60 % ( over 35 million ) of the 57 million deaths global. Given the global population distribution, about 80 % of deaths due to chronic NCDs worldwide now occur in abject and middle income countries, while merely 20 % occur in higher income countries. National economies are reportedly suffering significant losses because of premature deaths or inability to work resulting from heart disease, stroke and diabetes. For example, China is expected to lose roughly $ 558 billion in national income between 2005 and 2015 due to early deaths. In 2005, kernel disease, stroke and diabetes caused an calculate loss in international dollars of national income of 9 billion in India and 3 billion in Brazil. [ 8 ]

absenteeism and presenteeism

The burden of chronic NCDs including mental health conditions is felt in workplaces around the populace, notably due to exalted levels of absenteeism, or absence from work because of illness, and presenteeism, or productiveness lost from staff coming to work and performing below normal standards due to poor health. For example, the United Kingdom experienced a personnel casualty of about 175 million days in 2006 to absence from illness among a working population of 37.7 million people. The estimate cost of absences due to illness was over 20 billion pounds in the same year. [ 9 ] The monetary value due to presenteeism is probable even larger, although methods of analyzing the economic impacts of presenteeism are even being developed. Methods for analyzing the clear-cut workplace impacts of NCDs versus early types of health conditions are besides still being developed .

Key diseases


For the huge majority of cancers, hazard factors are environmental or lifestyle-related, frankincense cancers are by and large preventable NCD. [ 10 ] Greater than 30 % of cancer is preventable via avoiding risk factors including : tobacco, being overweight or fleshiness, low fruit and vegetable intake, forcible inaction, alcohol, sexually impart infections, and air pollution. [ 11 ] infectious agents are responsible for some cancers, for case about all cervical cancers are caused by human papillomavirus infection .

cardiovascular disease

The first studies on cardiovascular health were performed in 1949 by Jerry Morris using occupational health data and were published in 1958. [ 12 ] The causes, prevention, and/or discussion of all forms of cardiovascular disease remain active fields of biomedical research, with hundreds of scientific studies being published on a weekly basis. A swerve has emerged, peculiarly in the early 2000s, in which numerous studies have revealed a connect between debauched food and an addition in heart disease. These studies include those conducted by the Ryan Mackey Memorial Research Institute, Harvard University and the Sydney Center for Cardiovascular Health. many major fast food chains, peculiarly McDonald ‘s, have protested the methods used in these studies and have responded with healthier menu options. A fairly recent vehemence is on the radio link between low-grade ignition that hallmarks atherosclerosis and its potential interventions. C-reactive protein ( CRP ) is a common inflammatory marker that has been found to be give in increase levels in patients at risk for cardiovascular disease. [ 13 ] besides osteoprotegerin which involved with regulation of a samara incendiary recording divisor called NF-κB has been found to be a risk factor of cardiovascular disease and mortality. [ 14 ] [ 15 ]


Type 2 Diabetes Mellitus is a chronic condition which is largely preventable and accomplishable but difficult to cure. Management concentrates on keeping blood boodle levels as close to normal ( “ euglycemia ” ) as possible without presenting undue affected role danger. This can normally be with conclusion dietary management, exercise, and use of appropriate medications ( insulin only in the case of type 1 diabetes mellitus. oral medications may be used in the case of type 2 diabetes, vitamin a good as insulin ). affected role department of education, sympathize, and participation is critical since the complications of diabetes are far less common and less severe in people who have well-managed lineage sugar levels. [ 16 ] [ 17 ] Wider health problems may accelerate the deleterious effects of diabetes. These include smoking, elevated cholesterol levels, fleshiness, high blood imperativeness, and lack of even use .

Chronic kidney disease

Although chronic kidney disease ( CKD ) is not presently identified as one of WHO ‘s main targets for global NCD command, there is compelling evidence that CKD is not only common, harmful and treatable but besides a major contributing component to the incidence and outcomes of at least three of the diseases targeted by WHO ( diabetes, high blood pressure and CVD ). [ 18 ] CKD powerfully predisposes to high blood pressure and CVD ; diabetes, high blood pressure and CVD are all major causes of CKD ; and major risk factors for diabetes, high blood pressure and CVD ( such as fleshiness and smoke ) besides cause or exacerbate CKD. In addition, among people with diabetes, high blood pressure, or CVD, the subset who besides have CKD are at highest gamble of adverse outcomes and high health care costs. therefore, CKD, diabetes and cardiovascular disease are closely consociate conditions that often coexist ; share common hazard factors and treatments ; and would benefit from a coordinated global approach to prevention and operate .

chronic respiratory disease

Main Article: Chronic respiratory disease

Chronic Respiratory Diseases ( CRDs ) are diseases of the lungs and airways. According to the World Health Organization ( WHO ) hundreds of millions of people suffer daily from CRDs. [ 19 ] Common CRDs are : Asthma, Chronic obstructive pneumonic disease, Occupational lung disease, and Pulmonary high blood pressure. [ 20 ] While CRDs are not curable, versatile treatments are available to help improve choice of life for individuals who have them. Most treatments involve dilating major airways to improve shortness of breath among other symptoms. [ 20 ] The independent risk factors for developing CRDs are : tobacco smoking, indoor and outdoor air befoulment, allergens, and occupational risks. [ 19 ] WHO helped launch the ball-shaped Alliance against Chronic Respiratory Diseases ( GARD ) in 2006. [ 21 ] GARD is voluntarily composed of national and external organizations and works toward “ reducing the ball-shaped effect of chronic respiratory diseases ” and focus chiefly on vulnerable populations and low and middle-income countries. [ 21 ] [ 22 ]

See besides


promote read

  • Lower GM, Kanarek MS; Kanarek (June 1982). “The mutation theory of chronic, noninfectious disease: relevance to epidemiologic theory”. Am. J. Epidemiol. 115 (6): 803–17. PMID 7046429.

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