Peyronie’s Disease: Symptoms, Diagnosis & Treatment

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Oral Drugs

Drug therapy may help men who are badly affected by the disease during the acute phase. Most society guidelines do not recommend oral drugs because long-run studies have not shown convincing benefit .

Oral vitamin E

Vitamin E is an antioxidant that is popular because of its balmy side effects and low monetary value. Studies as far back as 1948 picture that taking vitamin einsteinium may make plaques smaller and help straighten the penis. But most of these studies did not compare a group of people using vitamin e to a group of people who did not ( a control group ). A few studies of vitamin E that used a control group suggest that vitamin E does n’t work better than placebo. ( A placebo is a pill with no drugs in it – a “ sugar pill. ” )

Potassium amino-benzoate

small studies with placebo controls show that this vitamin B-complex help reduce brass size, but not the curve. unfortunately, it is dearly-won and patients need to take 24 pills per day for 3 to 6 months. It besides can upset your stomach, so many men stop taking it.


This non-steroidal, anti-estrogen drug has been used to treat desmoid tumors, which are like the plaques in Peyronie ‘s disease. There are merely a few operate studies of this drug and they have n’t shown that estrogen antagonist works better than placebo .


Colchicine is an anti-swelling agent that has been shown to be slightly helpful in a few little studies without controls. many patients taking colchicine get stomach problems and stop taking the drug. It has n’t been proven to work better than placebo .


Carnitine is an antioxidant drug that lowers swelling to help wounds heal. Studies without controls show some profit. But a holocene controlled study did n’t show it to work better than placebo .

Penile Injections

Injecting a drug right into the plaque brings higher doses of the drug to the trouble than when a drug is taken by mouth. Plaque injection is much used for men with early Peyronie ’ south disease or those who are n’t surely they want to have operation. The bark is often numbed before the tear to reduce pain .

Verapamil injections

Verapamil is by and large used to treat high rake imperativeness. Some studies suggest that verapamil injection may work for penile annoyance and arch. Verapamil appears to be a estimable, low-cost option for the treatment of Peyronie ‘s disease. More control studies are needed to prove how well it works .

Interferon injections

Interferon is a protein made in the soundbox that helps control swelling. It has been shown to help control scarring, possibly by slowing down the rate that scratch weave builds and by making an enzyme that breaks down the scar tissue. A large-scale test of interferon injection for Peyronie ‘s disease showed that this treatment might help .

Collagenase injections

Collagenase is made in the body and breaks down certain scar tissues. Studies have shown that injecting collagenase into plaques helped fix Peyronie ‘s disease. This drug is now approved in the U.S. by the FDA for treatment of men with penises curving more than 30 degrees.

Other Treatments

other ways to treat Peyronie ‘s disease are being studied. But there is n’t enough data on them yet to prove they work. Some little studies have shown that stretching the penis daily for at least 6 months may help restore distance and wind. Treating the penis with sonography, radiation sickness, shockwaves, heating system and verapamil on the skin are besides being studied. These, for the most part, are not proven and are not recommended by experts in the discipline .

Surgery for Peyronie’s Disease

operating room is reserved for men with more severe, disabling penile deformities that make it hard to have sexual activity. Most health care providers suggest putting off operation until the brass and curving have stopped getting worse and the patient has shown no worsening for at least 9 to 12 months. Before operating room, your health wish supplier may check the blood flow in the penis by injecting a drug that will make it starchy and may besides look at the inside of the penis using ultrasound. These tests help show what is going on inside your penis ( such as whether there is besides ED ) sol your health wish provider can decide which type of operating room is best for you. There are 3 basic ways to fix Peyronie ‘s disease with surgery :

  • making the side of the penis opposite the plaque shorter
  • making the side of the penis that curves longer
  • placing a prosthetic device inside the penis if the man has both Peyronie’s disease and erectile dysfunction
Surgery to Shorten the Side of the Penis Opposite the Plaque/Curve

This character of surgery can be done either by cutting out small pieces of tissue on the outside of the curve and sewing it closed or by folding the weave and pulling it together with surgical train of thought. The operation is most frequently dependable, easy for the surgeon to do and has a humble risk of problems ( such as bleeding or making ED worse ). A drawback is that this type of surgery can make the penis short. This surgery is better for men with mild or no ED, mild-to-moderate penile wind and a long penis .

Surgery to Make the Side of the Penis that is Curved Longer

This type of surgery is used when the penile curve is severe, the plaque becomes calcified or the cock has become identical narrow. The surgeon cuts the plaque to ease tension and may remove some of the brass. The distance that is left is then filled with a graft. In most cases, this surgery will not make the penis much light. But it is harder for the surgeon to do and there is a risk it could make ED worse. This surgery is much entirely recommended for cases of severe deformity in men who are able to get erections hard enough for arouse .

Penile Prosthetic Devices

An inflatable pump or ductile silicone rods placed inside the penis are effective options for men with Peyronie ‘s disease and moderate-to-severe ED. In most cases, this will straighten the penis and allow it to get stiff enough for sex. If the device does n’t straighten the penis enough, the surgeon may straighten it more by modeling the brass against the cadaver prosthesis or by cutting the brass and using a graft to cover the open .

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