little intestinal bacterial overgrowth ( SIBO ) occurs when there is an abnormal increase in the overall bacterial population in the belittled intestine — particularly types of bacteria not normally found in that part of the digestive tract. This circumstance is sometimes called blind loop syndrome .
SIBO normally results when a circumstance — such as surgery or disease — slows the passage of food and pine away products in the digestive tract, creating a breed reason for bacteria. The excess bacteria often cause diarrhea and may cause burden loss and malnutrition .
While SIBO is often a complication of stomach ( abdominal ) operation, this condition can besides result from structural problems and some diseases. sometimes operating room is needed to correct the problem, but antibiotics are the most common treatment.
Signs and symptoms of SIBO often include :
- Loss of appetite
- Abdominal pain
- An uncomfortable feeling of fullness after eating
- Unintentional weight loss
When to see a doctor
Bloating, nausea and diarrhea are signs and symptoms of many intestinal problems. See your doctor for a broad evaluation — specially if you ‘ve had abdominal operating room — if you have :
- Persistent diarrhea
- Rapid, unintentional weight loss
- Abdominal pain lasting more than a few days
If you have severe abdominal pain, seek contiguous checkup caution .
There is a problem with information submitted for this request. Review/update the information highlighted below and resubmit the form .
Get the latest health information from Mayo Clinic delivered to your inbox.
Subscribe for free and receive your in-depth guide to digestive health, plus the latest on health innovations and newsworthiness. You can unsubscribe at any time .
ErrorEmail field is required
ErrorInclude a valid e-mail address
First Name (let us know your preferred name)
To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your electronic mail and web site custom information with other data we have about you. If you are a Mayo Clinic patient, this could include protect health information. If we combine this information with your protected health information, we will treat all of that information as protect health information and will only use or disclose that information as set away in our notice of privacy practices. You may opt-out of electronic mail communications at any time by clicking on the unsubscribe yoke in the electronic mail .
Thank you for subscribing
Your in-depth digestive health steer will be in your inbox soon. You will besides receive emails from Mayo Clinic on the latest health newsworthiness, inquiry, and care.
Read more: ED
If you don ’ thyroxine receive our e-mail within 5 minutes, check your SPAM folder, then contact us at newsletters @ mayoclinic.com .
Sorry something went wrong with your subscription
Please, sample again in a copulate of minutes
Your digestive tract stretches from your talk to your anus. It includes the organs necessary to digest food, absorb nutrients and summons waste .
belittled intestinal bacterial overgrowth ( SIBO ) can be caused by :
- Complications of abdominal surgery, including gastric bypass for obesity and gastrectomy to treat peptic ulcers and stomach cancer
- Structural problems in and around your small intestine, including scar tissue (intestinal adhesions) that can wrap around the outside of the small bowel, and bulging pouches of tissue that protrude through the wall of the small intestine (intestinal diverticulosis)
- Certain medical conditions, including Crohn’s disease, radiation enteritis, scleroderma, celiac disease, diabetes or other conditions that can slow movement (motility) of food and waste products through the small intestine
Why small intestinal bacterial overgrowth (SIBO) develops
The small intestine is the longest section of your digestive nerve pathway, measuring about 20 feet ( 6.1 meters ). The humble intestine is where food mixes with digestive juices and nutrients are absorbed into your bloodstream .
Unlike your big intestine ( colon ), your small intestine normally has relatively few bacteria due to rapid flow of contents and the presence of bile. But in SIBO, dead food in the bypass little intestine becomes an ideal breeding labor for bacteria. The bacteria may produce toxins adenine well as interfere with the absorption of nutrients. The breakdown products following bacterial digestion of food can besides trigger diarrhea .
Factors that increase your gamble of SIBO include :
- Gastric surgery for obesity or ulcers
- A structural defect in the small intestine
- An injury to the small intestine
- An abnormal passageway (fistula) between two segments of bowel
- Crohn’s disease, intestinal lymphoma or scleroderma involving the small intestine
- History of radiation therapy to the abdomen
- Diverticulosis of the small intestine
- Adhesions caused by previous abdominal surgery
little intestinal bacterial overgrowth ( SIBO ) can cause escalating problems, including :
Poor absorption of fats, carbohydrates and proteins. Bile salts, which are normally needed to digest fats, are broken down by the surfeit bacteria in your small intestine, resulting in incomplete digestion of fats and diarrhea. bacterial products may besides harm the mucous line ( mucous membrane ) of the belittled intestine, resulting in decreased absorption of carbohydrates and proteins .
Bacteria can compete for available food. And compounds produced through the bacterial break-down of dead food can besides trigger diarrhea. together, these effects of bacterial overgrowth result in diarrhea, malnutrition and weight unit loss .
Vitamin deficiency. As a result of incomplete absorption of fats, your consistency ca n’t in full absorb the fat-soluble vitamins A, D, E and K. Bacteria in the belittled intestine synthesize adenine well as use vitamin B-12, which is essential for the normal function of your anxious organization and the production of blood cells and DNA.
Read more: Gastritis – Symptoms and causes
The overgrowth of bacteria can result in B-12 insufficiency that can lead to helplessness, tire, tickling, and numbness in your hands and feet and, in advanced cases, to mental confusion. damage to your central nervous system resulting from B-12 insufficiency may be irreversible .
- Weakened bones (osteoporosis). Over time, damage to your intestine from abnormal bacterial growth causes poor calcium absorption, and eventually may lead to bone diseases, such as osteoporosis.
- Kidney stones. Poor calcium absorption may also eventually result in kidney stones.