Hypercalcemia – Diagnosis and treatment – Mayo Clinic


Because hypercalcemia can cause few, if any, signs or symptoms, you might not know you have the disorderliness until routine blood tests reveal a high grade of blood calcium. rake tests can besides show whether your parathyroid gland hormone level is high, indicating that you have hyperparathyroidism .
To determine if your hypercalcemia is caused by a disease such as cancer or sarcoidosis, your doctor of the church might recommend imaging tests of your bones or lungs .


If your hypercalcemia is mild, you and your doctor of the church might choose to watch and wait, monitoring your bones and kidneys over time to be sure they remain healthy.

For more hard hypercalcemia, your repair might recommend medications or treatment of the underlying disease, including operating room .


In some cases, your repair might recommend :

  • Calcitonin (Miacalcin). This hormone from salmon controls calcium levels in the blood. Mild nausea might be a side effect.
  • Calcimimetics. This type of drug can help control overactive parathyroid glands. Cinacalcet (Sensipar) has been approved for managing hypercalcemia.
  • Bisphosphonates. Intravenous osteoporosis drugs, which can quickly lower calcium levels, are often used to treat hypercalcemia due to cancer. Risks associated with this treatment include breakdown (osteonecrosis) of the jaw and certain types of thigh fractures.
  • Denosumab (Prolia, Xgeva). This drug is often used to treat people with cancer-caused hypercalcemia who don’t respond well to bisphosphonates.
  • Prednisone. If your hypercalcemia is caused by high levels of vitamin D, short-term use of steroid pills such as prednisone are usually helpful.
  • IV fluids and diuretics. Extremely high calcium levels can be a medical emergency. You might need hospitalization for treatment with IV fluids and diuretics to promptly lower the calcium level to prevent heart rhythm problems or damage to the nervous system.

Surgical and other procedures

Problems associated with hyperactive parathyroid gland glands often can be cured by operating room to remove the tissue that ‘s causing the problem. In many cases, only one of a person ‘s four parathyroid gland glands is affected. A especial scan test uses an injection of a small venereal disease of radioactive substantial to pinpoint the gland or glands that are n’t working properly .


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More Information

  • Hemodialysis
  • Peritoneal dialysis

Clinical trials

explore Mayo Clinic studies testing newly treatments, interventions and tests as a mean to prevent, detect, treat or pull off this condition .

Preparing for your appointment

You might start by seeing your basal care provider. however, you ‘ll likely be referred to a doctor of the church who specializes in treating hormonal disorders ( endocrinologist ) .
here ‘s some information to help you get ready for your appointment .

What you can do

Before your appointment, make a list of :

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  • Your symptoms, including those that seem unrelated, and when they began
  • Key personal information, including major stresses or recent life changes, medical history, and family medical history
  • All medications, vitamins and other supplements you take, including doses
  • Questions to ask your doctor

Take a class member or friend along, if potential, to help you remember the information you ‘re given .
For hypercalcemia, basic questions to ask your doctor include :

  • What’s the most likely cause of my symptoms?
  • What tests do I need?
  • What treatments are available, and which do you recommend?
  • What side effects can I expect from treatment?
  • Are there alternatives to the primary approach that you’re suggesting?
  • I have other health conditions. How can I best manage them together?

What to expect from your doctor

Your repair is likely to ask you questions, including :

  • Does anything improve your symptoms?
  • What, if anything, worsens your symptoms?
  • Have you had kidney stones, bone fractures or osteoporosis?
  • Do you have bone pain?
  • Do you have unexplained weight loss?
  • Have family members had hypercalcemia or kidney stones?
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